This book brings together 27 state-of-the-art, refereed and subsequently revised, research and review papers, by leading experts and practitioners in mathematical methods in biomedical imaging, in intensity-modulated radiation therapy (IMRT) and in optimization and inverse problems. The emphasis is on trying to discover relations and connections between these fields that will enhance progress in each of them. As this volume shows, applicable mathematical work in these fields goes hand-in-hand with real-world applications and the mutual “technology transfers” between them leads to further progress.
This book covers various aspects of modern microscopy, with emphasis on multidimensional (three-dimensional and higher) and multimodality microscopy. The idea of compiling an authoritive and comprehensive book on modern microscopies was first discussed during the 8th International Conference on 3D Image Processing in Microscopy and the 7th International Conference on Confocal Microscopy. We were greatly encouraged by leading experts in the areas, and fortunately honored by their commitments in contributing chapters.
Given the rapid pace at which the field is evolving and expanding, we soon realized that the size of the book made it necessary to be in two volumes. In the first volume, the topics include multiphoton fluorescent microscopy, confocal microscopy, x-ray microscopy and microtomography, electron microscopy, probe microscopy and multidimensional image processing for microscopy. In the second volume, there are chapters demonstrating typical microscopical applications, both biological and material. The readership covers researchers in life sciences, optics, microscopy and image processing. Engineers and technologists should also find the content valuable.
The editorial process of these two volumes has been arduous and pleasant. We would like to acknowledge Ms. Tung Yu-chi and Mr. M. S. Park for their assistance on word processing. We are particularly grateful to institute of Zoology, Academia Sinica, National Science Council, Republic of China, the Electron Microscopy Society of the Republic of China, and State University of New York for organizing the conference and financial support.